Name
anti-Histone Methyltransferase (SUV39H1) Antibody
Size
Histone Methyltransferase (SUV39H1) Antibody
Catalog number
3942-100
Price
316 EUR
More details
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Target of this antibody:
HMT (SUV39H1)
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Alternative names of antibody target:
Histone-lysine N-methyltransferase, SUV39H1, Histone H3-K9 methyltransferase 1, H3-K9-HMTase 1, Full=Position-effect variegation 3-9 homolog, Suppressor of variegation 3-9 homolog 1, Su(var)3-9 homolog 1
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Background information:
The histone methyltransferase KMT1A / SUV39H1 is the mammalian homologue of the Drosophila PEV modifier Su(var)3-9 protein. SUV39H1 contains the SET and chromo domains. In eukaryotic cells, SUV39H1 and the methyl-lysine binding protein HP1 interact to repress transcription at heterochromatic sites. SUV39H1 methylates histone H3 on lysine 9, which generates a binding site for HP1 proteins that plays a role in heterochromatin formation and gene silencing.
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Antibody host:
Rabbit
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Clonality of antibody:
Polyclonal
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Isotype:
Rabbit IgG
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This antibody reacts with:
Human, mouse, rat, drosophila
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Immunogene sequence:
Synthetic peptide surrounding amino acid 389 of mouse Histone Methyltransferase.
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Concentration of antibody:
0.5 mg/ml
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Form of antibody:
Liquid
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Formulation of this antibody:
100 µg (0.5 mg/ml) affinity purified rabbit anti-Histone transferase polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
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Purification method:
Affinity purified
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This antibody has been succesfully tested for use in following methods:
Western blot
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Recommended usage:
Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. 3T3 cell lysate can be used as a positive control.
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Storage information:
Shelf time: 12 months in temp.: -20 deg.C
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Shipping conditions:
gel pack
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How to handle this antibody:
The antibody solution should be gently mixed before use.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps